Federal / challenges / Grant
NIA SBIR / PA-27-100
Application routeUp to $500,000 Phase I; $2.5m Phase II for non-AD/ADRD projects
Timing in the source map: Next listed deadline: 5 January 2027; earliest listed start July 2027
Qualification: Eligible U.S. small business, credible PI and meaningful company research. Budget is mission- and scope-dependent.
Next step: Define one testable enabling technology and discuss it with NIA before drafting.
Source-map snapshot: 15 October 2026 · not a live eligibility determinationFederal / challenges / Grant
NIA STTR / PA-27-102
Application routeNIA mission-specific ceilings; not an automatic award
Timing in the source map: Next listed deadline: 5 January 2027; earliest listed start July 2027
Qualification: At least 40% of research/analytical effort at the business and 30% at one research institution; full eligibility rules apply.
Next step: Use this route for a genuine university-dependent research collaboration, not a pass-through arrangement.
Source-map snapshot: 15 October 2026 · not a live eligibility determinationFederal / challenges / Grant
NSF SBIR/STTR / NSF 26-510
Invitation requiredUp to $305,000 Phase I; $1.25m Phase II
Timing in the source map: Listed full deadlines: 4 November 2026 and 4 March 2027
Qualification: Project Pitch invitation and substantial technical risk in a genuinely novel technology.
Next step: Confirm invitation and proposal readiness; do not treat a website or routine consulting service as the innovation.
Source-map snapshot: 15 October 2026 · not a live eligibility determinationFederal / challenges / R&D award
ARPA-H Health Science Futures
Rolling routeProject-specific, negotiated
Timing in the source map: Mission-office summary route described in the source map
Qualification: Transformative technical program, credible team and measurable milestones; required summary and feedback gates.
Next step: Align with a concrete measurement or predictive-model advance and confirm current instructions.
Source-map snapshot: 15 October 2026 · not a live eligibility determinationFederal / challenges / R&D award
ARPA-H Proactive Health
Rolling routeProject-specific, negotiated
Timing in the source map: Mission-office summary route described in the source map
Qualification: A concrete prevention or functional-decline outcome; mission fit matters more than general aging language.
Next step: Develop a technically credible concept and obtain the required written feedback before a full proposal.
Source-map snapshot: 15 October 2026 · not a live eligibility determinationFederal / challenges / Contract / prototype
MTEC FY2026 multi-topic request
Deadline listedTopic- and negotiation-dependent
Timing in the source map: 9 October amendment; listed due date 30 October 2026
Qualification: Military-medical relevance, full topic requirements and consortium qualifications. New focus area concerns trauma-related lung/kidney biomarkers.
Next step: Review the complete request and determine whether a qualified prime needs a discrete analysis contribution.
Source-map snapshot: 15 October 2026 · not a live eligibility determinationFederal / challenges / Challenge award
J&J Human Model Systems QuickFire
Full terms need checkingUp to $100,000 advertised award funding
Timing in the source map: Sponsor announcement lists 23 October 2026 deadline
Qualification: Scalable human-relevant models; Singapore ecosystem interest. The advertised pool is not a guaranteed amount for every winner.
Next step: Check the sponsor’s complete challenge terms and existing model/team readiness before applying.
Source-map snapshot: 15 October 2026 · not a live eligibility determinationFederal / challenges / Commercial contract
Already-funded laboratory / CRO procurement
No named open bidQuote a defined work package
Timing in the source map: Customer-specific procurement rather than a grant application
Qualification: A real budgeted need, supplier approval, allowable scope and contract terms.
Next step: Find a funded project with a specific analysis or study-operations requirement; no buyer need is assumed here.
Source-map snapshot: 15 October 2026 · not a live eligibility determinationFederal / challenges / Contract / prototype
DARPA BTO opportunities
WatchlistCall-specific
Timing in the source map: Identified FY2026 BTO call expired 30 September 2026
Qualification: Live notice and national-security relevance are essential; not a general open aging grant.
Next step: Look for a current responsive call instead of recycling an expired announcement.
Source-map snapshot: 15 October 2026 · not a live eligibility determinationFederal / challenges / R&D award
ARPA-H small-business 2026 round
Closed in source snapshotTopic-specific
Timing in the source map: Solution-summary gate was 17 July; later gates September/October 2026
Qualification: New applicants cannot assume they can join a closed round.
Next step: Check future topics or an appropriate rolling mission-office route; do not budget an unawarded grant.
Source-map snapshot: 15 October 2026 · not a live eligibility determinationFederal / challenges / Challenge award
NIH NAMs Reduction to Practice Challenge
Restricted continuation$7m total competition pool in source map
Timing in the source map: Phase 2 Milestone 1 to 22 March 2027
Qualification: Continuation restricted to Phase 1 winners; the pool is not a typical award or a new-entrant opening.
Next step: A service role with an eligible team would require a real buyer and permitted contract.
Source-map snapshot: 15 October 2026 · not a live eligibility determinationFederal / challenges / Prize
XPRIZE Healthspan
No open late-entry spotsDo not model prize receipts
Timing in the source map: Finals-stage capacity limitation reported in the map
Qualification: Entry and trial costs can be substantial; no new Karam entry is established.
Next step: Consider a permitted service role only if an existing team has an actual requirement.
Source-map snapshot: 15 October 2026 · not a live eligibility determination