Evidence / Edition 01

THE CELLULAR
RESEARCH ATLAS.

The model. The finding. The gap. A source-linked map of recent research—built to distinguish a promising signal from a demonstrated outcome.

Regional views Methods & coverage

AI-generated cellular concept illustration

Concept illustration · not experimental data

New / CRISPR research & discovery

A new method layer for the Atlas.

The original 15-record cellular-aging collection remains intact. Explore 26 CRISPR and comparator records, including two shared sources—39 unique research and sponsor records across both collections.

Open CRISPR Atlas Target evidence

A cinematic molecular-and-climate scene with a CRISPR complex, cells and a planet.

14 Research papers01 Sponsor update2026 July 15–October 15Selected collection · Not a systematic review

2026-10-14 · United States

A different route to cellular reprogramming

Cells + animals

Cell-state signatures; senescence-associated features; mouse frailty and survival.

Nature Aging↗

2026-10-08 · China

Repair depends on the tissue’s metabolic context

Human observation + animals

Acute liver injury, metabolic regulation, and regenerative response.

Signal Transduction and Targeted Therapy↗

2026-10-08 · United States

An early human signal, reported by the sponsor

Early human study

Early safety observations and exploratory visual-function measures.

Life Biosciences — sponsor statement↗

2026-10-06 · Europe

The chemistry of membranes—not just the amount of fat

Cross-species + worms

Lipid-chain composition; worm lifespan; human genetic associations.

Nature Aging↗

2026-10-03 · Europe

A younger molecular state—after an identity change

Human cells in culture

Epigenetic age measures and acquisition of neural stem-cell identity.

Aging Cell↗

2026-10-01 · South Korea

Temporary instructions. A specific tissue.

Animal intervention

Regeneration and recovery after experimental acute liver injury.

Cell Reports Medicine↗

2026-09-29 · Europe

A membrane lipid connects to muscle function

Human observation + animals

Cardiolipin metabolism, mitochondrial function, and muscle phenotype.

Nature Aging↗

2026-09-25 · Japan

Target engagement is not the same as benefit

Human randomized trial

Blood NAD metabolites; hearing and physical-performance outcomes.

npj Aging↗

2026-09-21 · United States

Seeing cell states with more than one measurement

Animal tissue profiling

Spatial vibrational signatures, transcriptomic states, and senescence-associated tissue patterns.

Nature Aging↗

2026-09-17 · Europe

Senescence is not one uniform cell state

Human cells in culture

Cell morphology, transcriptional patterns, and treatment-response profiles.

npj Aging↗

2026-09-09 · South Korea

Can mechanics restore cultured-cell function?

Cells + animals

Proliferation, identity markers, stress readouts, and preclinical repair.

Small↗

2026-09-07 · China

When a younger clock may track disease recovery

Human trial reanalysis

Proteomic aging-clock estimates in previously collected clinical samples.

Nature Biotechnology↗

2026-09-03 · India

A human biomarker signal from India

Human randomized trial

Leukocyte telomere measurements, telomerase activity, and gene expression.

Mechanisms of Ageing and Development↗

2026-08-25 · China

One microbe. One metabolite. Several questions.

Human observation + animals

Human abundance associations; mouse intestinal, inflammatory, and functional outcomes.

Nature Aging↗

2026-08-24 · China

Protecting the blood-forming system

Cells + animals

Stem-cell stress, function, lipid remodeling, and mouse immune balance.

Blood↗

Publication dates refer to the first online publication checked, not necessarily the dates experiments or clinical enrollment occurred. Selected regional groupings use study context or lead affiliation; they do not identify Karam locations or partners.

Work with Karam