2026-10-14 · United States
A different route to cellular reprogramming
Cells + animalsCell-state signatures; senescence-associated features; mouse frailty and survival.
Nature Aging↗
Research / 2026 library
THE SOURCE
COMES FIRST.
Read the finding in its actual setting. Every brief identifies the model, endpoint, primary source, access level, and the next unanswered question.
Concept illustration · not experimental data
Fourteen papers. One sponsor update.
The collection includes null results, observational evidence, cell and animal experiments, a human trial reanalysis, and a clearly separated early sponsor report. It is not a comprehensive or independently replicated body of evidence.
2026-10-08 · China
Repair depends on the tissue’s metabolic context
Human observation + animalsAcute liver injury, metabolic regulation, and regenerative response.
Signal Transduction and Targeted Therapy↗
2026-10-08 · United States
An early human signal, reported by the sponsor
Early human studyEarly safety observations and exploratory visual-function measures.
Life Biosciences — sponsor statement↗
2026-10-06 · Europe
The chemistry of membranes—not just the amount of fat
Cross-species + wormsLipid-chain composition; worm lifespan; human genetic associations.
Nature Aging↗
2026-10-03 · Europe
A younger molecular state—after an identity change
Human cells in cultureEpigenetic age measures and acquisition of neural stem-cell identity.
Aging Cell↗
2026-10-01 · South Korea
Temporary instructions. A specific tissue.
Animal interventionRegeneration and recovery after experimental acute liver injury.
Cell Reports Medicine↗
2026-09-29 · Europe
A membrane lipid connects to muscle function
Human observation + animalsCardiolipin metabolism, mitochondrial function, and muscle phenotype.
Nature Aging↗
2026-09-25 · Japan
Target engagement is not the same as benefit
Human randomized trialBlood NAD metabolites; hearing and physical-performance outcomes.
npj Aging↗
2026-09-21 · United States
Seeing cell states with more than one measurement
Animal tissue profilingSpatial vibrational signatures, transcriptomic states, and senescence-associated tissue patterns.
Nature Aging↗
2026-09-17 · Europe
Senescence is not one uniform cell state
Human cells in cultureCell morphology, transcriptional patterns, and treatment-response profiles.
npj Aging↗
2026-09-09 · South Korea
Can mechanics restore cultured-cell function?
Cells + animalsProliferation, identity markers, stress readouts, and preclinical repair.
Small↗
2026-09-07 · China
When a younger clock may track disease recovery
Human trial reanalysisProteomic aging-clock estimates in previously collected clinical samples.
Nature Biotechnology↗
2026-09-03 · India
A human biomarker signal from India
Human randomized trialLeukocyte telomere measurements, telomerase activity, and gene expression.
Mechanisms of Ageing and Development↗
2026-08-25 · China
One microbe. One metabolite. Several questions.
Human observation + animalsHuman abundance associations; mouse intestinal, inflammatory, and functional outcomes.
Nature Aging↗
2026-08-24 · China
Protecting the blood-forming system
Cells + animalsStem-cell stress, function, lipid remodeling, and mouse immune balance.
Blood↗
Work with Karam
From evidence to a useful decision.
Evidence / Scope an engagement
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One question. A source trail. A decision you can explain.
Scope & deliverables↗
Data / Technical qualification required
Karam Data Review
Find out what your existing data can actually support.
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Studies / Laboratory agreement required
Karam Study Desk
A defined experiment, a comparable lab scope and a usable handover.
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