KARAMBIOSCIENCE
EST. 2026
EVIDENCE / 03
Evidence / Edition 01

BIOELECTRICITY EVIDENCE.

Five original-source records: human-derived cells, animal regeneration and computational modeling. Publication dates are preserved; review and clinical status remain separate.

AI-generated cellular concept illustration
Concept illustration · not experimental data
Bioelectricity / Function-first research

Bioelectricity evidence, with the limits attached.

Five sources published in 2016–2025 extend the existing collection. Together with the 15-record launch collection and 26 CRISPR/comparator records (two shared), the site now holds 44 unique scientific/sponsor records. Original publication dates remain unchanged. Human-cell experiments, animal experiments and simulations are identified separately.

New / CRISPR research & discovery

A new method layer for the Atlas.

The original 15-record cellular-aging collection remains intact. Explore 26 CRISPR and comparator records, including two shared sources—39 unique research and sponsor records across both collections.

A cinematic molecular-and-climate scene with a CRISPR complex, cells and a planet.
05Source records00Human clinical trials052016–2025 publicationsSelected collection · Not a systematic review
Interpretation rule

Study model is not a quality rating. Open a brief for the finding, limitation, and source-access level.

5 of 5 bioelectricity records

Self-organization and local neural-gap closure

2023-11-30 · Published experiment — human-derived cells in vitro

In-vitro gap coverage does not establish restoration of a functioning nervous system, clinical repair, or a bioelectric mechanism. Selection of stable bridges matters; donor replication is unresolved.

One donor. Conflicting clock estimates.

2025-06-06 · Published experiment — human-derived cells in vitro

Single-donor result; younger clock estimates do not prove durable rejuvenation, restored function or bioelectric causation. Composition, handling and configuration are potential confounders requiring tests.

Keratinocyte voltage and senescence

2025-08-07 · Published experiment — human-derived cells in vitro

Culture phenotypes and dye-based measures do not establish human rejuvenation or durable tissue restoration. Drug specificity, donor generalizability and long-term safety require separate tests.

BETSE: a computational framework

2016-07-06 · Published simulation

Conditional on equations, geometry, parameters and assumptions; not an aging clock or an Anthrobot rejuvenation validation.

Adult frog regeneration and function

2022-01-26 · Published animal experiment

A combined intervention in frogs; not a complete normal limb, a human therapy, or proof of voltage-specific causation.

Publication dates refer to the first online publication checked, not necessarily the dates experiments or clinical enrollment occurred. Selected regional groupings use study context or lead affiliation; they do not identify Karam locations or partners.

Work with Karam

From evidence to a useful decision.

Evidence / Scope an engagement

Karam Evidence Sprint

One question. A source trail. A decision you can explain.

Scope & deliverables↗
Data / Technical qualification required

Karam Data Review

Find out what your existing data can actually support.

Scope & deliverables↗
Studies / Laboratory agreement required

Karam Study Desk

A defined experiment, a comparable lab scope and a usable handover.

Scope & deliverables↗