Mitochondria

The distinction to keep

An energy-related biomarker may confirm that an intervention reached a pathway. A function test asks a different question. Both are useful, but one should not silently stand in for the other.

Questions for a useful brief

• Is the result a biochemical change or a functional benefit?
• Is the model naturally aged or experimentally deficient?
• What unintended costs were measured?

Build a decision—not a slogan

Write down the actual model and endpoint before deciding what the result implies. Then name the observation that would change your interpretation. The linked records below retain their original experimental setting and source-access limits.