KARAMBIOSCIENCE
EST. 2026
EVIDENCE / 02
Decision note 04

Mechanics without magic

A physical mechanism still needs careful controls.

AI-generated cellular concept illustration
Concept illustration · not experimental data

Start with the handling control

When cells are processed in a device, handling itself can alter the measured population. A sham comparison helps separate the intended intervention from transport, recovery time, and selection.

Count the missing cells

Improved averages among surviving cells may conceal substantial loss. Recovery, viability, and the distribution of responses belong beside any increase in a desirable marker.

Do not scale the claim beyond the experiment

An ex vivo cell-processing result does not establish a whole-person wellness intervention. A useful translation path starts with the exact cell population and manufacturing context studied.

Source-linked research

Sources to read alongside this note

Original publisher links and access limits are included in every brief. Artwork is conceptual, not a reproduction of study figures.